Preparation H Cream with Biodyne

Preparation H Cream with Biodyne (50g/ 1.75 oz)

$22.00 USD

Brands: Preparation H,


Preparation H Cream with Biodyne – New Formulation. Preparation H Cream has been reformulated slightly, but still contains biodyne. It may appear slightly different, but since the active ingredient remains the same, you should expect it to work in the same way.

Though marketed as an effective treatment for hemorrhoids, Preparation H Cream with Biodyne from Canada is also used to fight wrinkles and relieve under eye puffiness by those in the know. The ‘secret’ ingredient is biodyne (also known as Live Yeast Cell Derivative – LYCD).

Preparation H Cream found in the USA does not contain biodyne, which was removed when the product was reformulated years ago. Instead, it contains phenylephrine HCI 0.25 % – a vasoconstrictor that some dermatologists claim will constrict capillaries and temporarily reduce dark circles and puffy eyes. However, many individuals report irritation and burning when using the US version of Preparation H.

In the People’s Pharmacy Guide to Home and Herbal Remedies 1999 by Joe & Teresa Graedon,  the authors attest to the Canadian version of Preparation H  being used for many other indications besides hemorrhoids. For years, it has been used to treat bed sores, itchy surgical scars, burns, dry cracked fingers, and even wrinkles.

Why does Biodyne work?
There is data to suggest that LYCD accelerates wound healing and is biologically active on skin cells. In fact, a clinical study conducted at Shriners Hospitals for Children-Cincinnati Burns Institute, Ohio, demonstrated that topical application of LYCD  accelerated the wound healing of diabetic mice (100% wound closure with biodyne vs 31.4% without biodyne – a significant difference).

The active ingredient in biodyne has been isolated as a protein fraction containing a mixture of several peptides. And we already know that some peptides offer benefits to skin.

Used by those in the know
Listed in Diane Iron’s popular book “The World’s Best Kept Beauty Secrets”, Irons claims that many middle-aged celebrities use Preparation H to maintain their youthful looks. Some say that supermodels swear by it as a beauty essential They claim that this hemorrhoid cream gives them an instant lift when they are bothered by eye bags. Celebrities including Conan O’Brien and Miss USA, are purported to use Preparation H Cream with Biodyne from Canada.

Preparation H Cream with Biodyne also available as an ointment.



Contains: Yeast as a live cell derivative (Bio-Dyne: Skin Respiratory Factor) 1.0%.

Non-medicinal Ingredients: Butylated hydroxyanisole, cellulose, cetyl alcohol, citric acid, disodium edetate, glycerin, glyceryl monostearate, glycerol oleate, lanolin, parabens, petrolatum, propyl gallate, propylene glycol, simethicone emulsion, sodium benzoate, sodium lauryl sulfate, stearyl alcohol, water, xanthan gum.


Apply freely morning and night and after each bowel movement.
For Intrarectal Use: Before applying, remove protective cover from dispensing cap. Attach dispensing cap to tube. Lubricate dispensing cap well, then gently insert dispensing cap part way into the anus. Thoroughly cleanse dispensing cap after each use and replace protective cover. Also apply cream to external area. Children under 12 years of age: consult a doctor.

Additional information


50 g/1.7 oz, 25 g/0.9 oz


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